Phytochemical Screening of Cinnamon Bark (Cinnamomum burmanii) (C. Ness & T. Ness) C. Ness ex Blume Ethanol Extract and Antioxidant Activity Test with DPPH (2,2-diphenyl-1-picrylhydrazyl) Method.
Keywords:
Antioxidant, Cinnamon bark, DPPH, Free radical
Abstract
Cinnamon (Cinnamomum burmanii) is one of the spices that can be used as cosmetic preparations in the pharmaceutical industry because it contains potent antioxidants. Examples of cosmetic products containing cinnamon are body scrubs, body showers, and moisturizers. This study aimed to determine the antioxidant activity of cinnamon extract using the DPPH method. Cinnamon was extracted using the maceration technique with 96% ethanol solvent, and phytochemical screening was carried out. The results of phytochemical screening from cinnamon bark extract were alkaloids, saponins, tannins, triterpenoids, and flavonoids. Antioxidant activity obtained an IC50 value of 25.35 ppm. Based on these results, the cinnamon extract has a very strong antioxidant activity value.
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References
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[4] B. E. Al-Dhubiab, ‘Pharmaceutical applications and phytochemical profile of Cinnamomum burmannii’, Pharmacognosy reviews, vol. 6, no. 12, p. 125, 2012.
[5] A. Sangal, ‘Role of cinnamon as beneficial antidiabetic food adjunct: A review.’, Advances in Applied Science Research, vol. 2, no. 4, pp. 440–450, 2011.
[6] S. F. Susanti and Mufadzilah, ‘UJI AKTIVITAS ANTIMIKROBA EKSTRAK BUAH ASAM (TAMARINDUS INDICA L.) DENGAN VARIASI KONSENTRASI DALAM MENGHAMBAT PERTUMBUHAN BAKTERI STAPHYLOCOCCUS AUREUS’, Journals of Ners Community, vol. 12, no. 1, Art. no. 1, Jun. 2021.
[7] M. Ervina, Y. E. Nawu, and S. Y. Esar, ‘Comparison of in vitro antioxidant activity of infusion, extract and fractions of Indonesian Cinnamon (Cinnamomum burmannii) bark’, International Food Research Journal, vol. 23, no. 3, p. 1346, 2016.
[8] W. Herdwiani and E. S. Rejeki, ‘Determination of Cytotoxic Activity from Cinnamon Stem Bark for T47D Cell Culture’, Jurnal Farmasi Indonesia, vol. 12, no. 2, pp. 102–113, 2015.
[9] N. Nasri, V. E. Kaban, H. D. Syahputra, and D. Satria, ‘Aktivitas Antibakteri Ekstrak Etanol Daun Alpukat (Persea americana Mill) Terhadap Escherichia coli, Salmonella typhi, dan Pseudomonas aeruginosa’, Herbal Medicine Journal, vol. 5, no. 1, pp. 13–19, 2022.
[10] R. Y. Paramawidhita, U. Chasanah, and D. Ermawati, ‘Formulasi dan Evaluasi Fisik Sediaan Emulgel Tabir Surya Ekstrak Kulit Batang Kayu Manis (Cinnamomum burmannii)’, Jurnal Surya Medika (JSM), vol. 5, no. 1, pp. 90–99, 2019.
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[12] D. R. A. Muhammad, E. Tuenter, G. D. Patria, K. Foubert, L. Pieters, and K. Dewettinck, ‘Phytochemical composition and antioxidant activity of Cinnamomum burmannii Blume extracts and their potential application in white chocolate’, Food Chemistry, vol. 340, p. 127983, 2021.
[13] G. Sikand, P. Kris-Etherton, and N. M. Boulos, ‘Impact of functional foods on prevention of cardiovascular disease and diabetes’, Current cardiology reports, vol. 17, no. 6, pp. 1–16, 2015.
[14] M. Asif, ‘Chemistry and antioxidant activity of plants containing some phenolic compounds’, Chemistry international, vol. 1, no. 1, pp. 35–52, 2015.
[15] N. Nasri, V. E. Kaban, K. Gurning, H. D. Syahputra, and D. Satria, ‘Aktivitas Antibakteri Ekstrak Etanol Daun Pepaya (Carica papaya Linn.) Terhadap Bakteri Pseudomonas aeruginosa’, INSOLOGI: Jurnal Sains dan Teknologi, vol. 1, no. 3, Art. no. 3, Jun. 2022, doi: 10.55123/insologi.v1i3.438.
[16] P. O. M. Ditjen, ‘Farmakope Indonesia Edisi III’, DEPKES RI. Jakarta, 1979.
[17] M. Muhammad, N. Nasri, V. E. Kaban, D. Satria, and H. Cintya, ‘Antibacterial Potential Ethanol Extract of Papaya Leaves (Carica papaya Linn.) Towards Salmonella typhi’, BEST Journal (Biology Education, Sains and Technology), vol. 5, no. 2, pp. 265–270, 2022.
[18] Departemen Kesehatan RI, Materia Medika Indonesia Jilid I dan II. Jakarta: Direktorat Jendral Pengawasan Obat dan Makanan, 1977.
[19] R. I. Depkes, ‘Materia Medika Indonesia Jilid IV Cetakan Pertama’, Jakarta: Dirjen Pengawasan Obat dan Makanan, 1980.
[20] J. B. Harbone, ‘Metode Fitokimia: Penuntun Cara Modern Menganalisa Tumbuhan, Terjemah Padmawinata, K’, Dan Soediro, I., Edisi Ii, Penerbitan ITB, Bandung, 1987.
[21] P. Molyneux, ‘The use of the stable free radical diphenylpicrylhydrazyl (DPPH) for estimating antioxidant activity’, Songklanakarin J. sci. technol, vol. 26, no. 2, pp. 211–219, 2004.
[22] F. K. Juniarti Departemen Biokimia, ‘Analisis senyawa metabolit sekunder dari ekstrak metanol daun surian yang berpotensi sebagai antioksidan’, Makara Journal of Science, 2011.
[23] H. S. Chung and W. S. Woo, ‘A quinolone alkaloid with antioxidant activity from the aleurone layer of anthocyanin-pigmented rice’, Journal of natural products, vol. 64, no. 12, pp. 1579–1580, 2001.
[24] Vijayalaxmi, C. R. Thomas Jr, R. J. Reiter, and T. S. Herman, ‘Melatonin: from basic research to cancer treatment clinics’, Journal of Clinical Oncology, vol. 20, no. 10, pp. 2575–2601, 2002.
[25] M. Mor et al., ‘Indole-based analogs of melatonin: in vitro antioxidant and cytoprotective activities’, Journal of pineal research, vol. 36, no. 2, pp. 95–102, 2004.
[26] R. A. Sadeli, ‘Uji Aktivitas Antioksidan Dengan Metode DPPH (1, 1-Diphenyl-2-Picrylhydrazyl) Ekstrak Bromelain Buah Nanas (Ananas Comosus (L.) Merr.)’, Fakultas Farmasi, Universitas Sanata Dharma, Yogyakarta, 2016.
[27] N.-E. Es-Safi, S. Ghidouche, and P. H. Ducrot, ‘Flavonoids: hemisynthesis, reactivity, characterization and free radical scavenging activity’, Molecules, vol. 12, no. 9, pp. 2228–2258, 2007.
[28] D. Tristantini, A. Ismawati, B. T. Pradana, and J. G. Jonathan, ‘Pengujian aktivitas antioksidan menggunakan metode DPPH pada daun tanjung (Mimusops elengi L)’, in Seminar Nasional Teknik Kimia Kejuangan, 2016, p. 1.
Published
2023-01-10
How to Cite
Sirait, T. S., Arianto, A., & Dalimunthe, A. (2023). Phytochemical Screening of Cinnamon Bark (Cinnamomum burmanii) (C. Ness & T. Ness) C. Ness ex Blume Ethanol Extract and Antioxidant Activity Test with DPPH (2,2-diphenyl-1-picrylhydrazyl) Method. International Journal of Science, Technology & Management, 4(1), 254-259. https://doi.org/10.46729/ijstm.v4i1.739
Section
Articles
