Utilization Of Glycerol By Product From Transesterification Of Waste Cooking Oil As A Cosurfactant In Nanocream Preparation

  • Zulmai Rani magister farmasi USU
  • Julia Reveny Departement of Technology Formulation, Faculty of Pharmacy, Universitas Sumatera Utara, Medan, 20155, Indonesia
  • Urip Harahap Departement of Technology Formulation, Faculty of Pharmacy, Universitas Sumatera Utara, Medan, 20155, Indonesia
Keywords: Keywords: waste cooking oil , transesterification, glycerol, nanocream


Waste cooking oil (used cooking oil ) is oil derived from leftover cooking oil for frying food. Waste cooking oil is still considered as waste by some people and waste cooking oil that should not be suitable for consumption is sometimes still widely reused in food processing, this can endanger health and reduce the nutritional value of food. In order to be used and have economic value, it is overcome by synthesizing waste cooking oil into glycerol so it can be used as cosurfactant. Besides as cosurfactant, this waste cooking oil glycerol also can be used for various chemical industies, foods, cosmetics, and pharmaceuticals industries. For cosmetic preparation, it can make a nanocream preparation. The purpose of this research was to utilize waste cooking oil into a glycerol which is used as a cosurfactant, to characterize the synthesis results based on IR Spectroscopy data and to formulate it to nanocream preparation. The research was conducted in an experimentally by making glycerol from side product of waste cooking oil. Separating glycerol process conducted by transesterification reaction. Glycerol of waste cooking oil by product was characterized with IR Spectroscopy and evaluated include organoleptic, glycerol contents, density, viscosity, ash content, and moisture content. Formulation of nanocream preparation using 30% of Tween 80 as surfactant, glycerol by-product as cosurfactant 7,5% concentration, and 20% of VCO as oil phase. The nanocream preparation was measured for its particle size with the aim of being able to determine the particle size of the formula to form nanoparticle size. The results showed that glycerol of waste cooking oil by product shows the presence of OH, CH-aliphatic, C=O carbonyl and C-O. particle size of nanocream preparation obtained was 397,76 nm. Based on the result of this research, the conclusion is glycerol of waste cooking oil  by-product can form nano size with presence of glycerol as cosurfactant. The particle size of the nanocream preparation obtained was still in the nanocream requirement range, namely 20-500 nm.




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Abdulkarim, M. F., Abdullah, G. Z., Chitneni, M., Mahdi, E. S., Yam, M. F., Faisal, A. (2010). Formulation and Characterization of Palm Oil Esters Based Nanocream for Topical Delivery of Piroxicam. International Journal of DrugDelivery. 2 : 287-298.

AOAC. (1995). Meth Official Methods of Analysis of The Association of Analytical Chemists. Washington D.C.

Appleby, D.B, (2005). Gliserol on The Biodiesel Handbook. AOCS Press.

Arita, S., Dara, M. B., & Irawan, J. (2008). Making Fatty Acid Methyl Esters from Cpo Off Grade With Esterification-Transesterification Method. Journal of Chemical Engineering, 15(2), 3443.

Aziz, I. (2007). Kinetic Transesterification Reaction of Waste cooking oil . Journal of Chemistry VALENSI, 1(1), 1923.

Aziz, I., Nurbayti, S., & Luthfiana, F. (2008). Purification of Glycerol from Biodiesel Making By-Product Using Waste cooking oil as Raw Material. Journal of Chemistry VALENSI, 1(3).

Aziz, I., Nurbayti, S., & Suwandari, J. (2013). Making Glycerol With Hydrolysis Reaction of Waste cooking oil . Chemistry Progress, 6(1).

Ditjen POM RI. (1995). Indonesian Pharmacopoeia. Edisi IV. Jakarta: Department of Health of Republic of Indonesia.

Hermanto, V.C. (2016). Making Kojic Acid Dipalmitate Nanocream With Combination of Surfactant Tween 80 and Cosurfactant Polyethylene Glicol 400 Using Mixer. Thesis. Faculty of Pharmacy. Sanata Dharma University. Yogyakarta.

Julianus, D. (2006). Optimization of Biodiesel Making Process from Waste cooking oil . Department of Chemical Engineering, UKI Paulus, Makassar

Kaplan, A.B. H., Cetin, M., Orgul, D., Hacimufnewlu, A., dan Hekimoglu, S. (2019). Formulation and In Vitro Evaluation of Topical Nanoemulsion based Gels Containing Daidzein. Journal of Drug Delivery Science and Technology (19) : 30263.

M. Pagliaro dan M. Rossi. (2008). The Future of Glycerol: New Uses of a Versatile Raw Material. RSC Green Chemistry Book Series.

Priani, S. E., Wulan, K., Amila, G. (2018). Formulation of Microemulsion Preparation Anti-Acne Gel Contains a Combination of Black Cumin Oil and Olive Oil. Scientific Journal of Pharmacy. Pharmacy Study Program, Islamic University of Bandung (UNISBA), Bandung.

SNI (1995). Standarisasi Nasional Indonesia. SNI 06-1564-1995: Crude Glycerol. National Standardization Council. Jakarta.

Suhery, W., Mira, F., dan Ivone, P. (2018). Formulation of Microemulsion from Combination of Pure Coconut Oil and Rice Bran Oil as Hair Fertilizer. Traditional Medicine Journal. Riau Collage of Pharmacy.

Wijaya, S., Arthawan, A.I., dan Sari, A.Novita. (2012). Potential of Coconut Sap as Bioethanol Raw Material. Bumi Lestari Journal. Vol. 12. No. 1. Department of Agricultural Engineering. Udayana University.

Wardana, D., Ahmad, R., Dinda, P. dan Ediyanto. (2019). Utilization of Glycerol from Used Oil as Ester Glycerol Surfactant. IJCST UNIMED. Department of Chemistry FMIPA. Medan.

How to Cite
Rani, Z., Julia Reveny, & Urip Harahap. (2021). Utilization Of Glycerol By Product From Transesterification Of Waste Cooking Oil As A Cosurfactant In Nanocream Preparation . International Journal of Science, Technology & Management, 2(4), 1258-1264. https://doi.org/10.46729/ijstm.v2i4.264