Antibacterial Activity Of Daemonorops Draco (Willd) Blume Fruit Ethanol Extract Against Some Bacterial Pathogens

  • Aida Apriani Postgraduate Programs, Faculty of Pharmacy, Universitas Sumatera Utara, Jl. Tri Dharma No. 5, Kampus USU, Medan. Sumatera Utara, Indonesia 20155.
  • Masfria Masfria Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Universitas Sumatera Utara, Jl. Tri Dharma No. 5, Kampus USU, Medan. Sumatera Utara, Indonesia 20155.
  • Panal Sitorus Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Universitas Sumatera Utara, Jl. Tri Dharma No. 5, Kampus USU, Medan. Sumatera Utara, Indonesia 20155.
Keywords: Daemonorops draco(Willd.) Blume, Maceration, Antibacterial, Staphylococcus aureus, Escherichia coli, Salmonella typhi.

Abstract

Daemonorops draco (Willd.) Blume fruit has been used as a traditional medicine which is well-known as an antiseptic,
stimulates blood circulation, anti-microbial, anti-viral, anti-tumor, wound medicine, diarrhea, fractures, gonorrhea,
minor burns and others. Daemonorops draco (Willd.) Blume belonging to the Arecaceae tribe contains a class of
chemical compounds such as alkaloids, flavonoids, tannins, saponins, steroids/triterpenoids, and glycosides. Flavonoid
compounds, saponins and tannins are chemical compounds that have potential as antibacterial and antiviral. This study
aims to determine the characteristics of simplicia, phytochemical screening, antibacterial activity test of the ethanol
extract of Daemonorops draco (Willd.) Blume fruit.Simplicia characterization includes organoleptic, macroscopic,
microscopic examination, determination of water content. Extraction was carried out by maceration using ethanol as a
solvent. Phytochemical screening was carried out on simplicia powder, fruit ethanol extract Daemonorops draco (Willd.)
Blume, assay of antibacterial activity of extract using diffusion methodagar by observing the zone of inhibition against
several test bacteria: Staphylococcus aureus, Escherichia coli, Salmonella thypi. The results of simplicia
characterization obtained water content of 4.65%. The results of the phytochemical screening test of simplicia and
ethanolic extracts contained groups of alkaloids, flavonoids, glycosides, saponins, tannins, steroids/triterpenoids. Having
the highest antibacterial activity was ethanol extract from Gram positive Staphylococcus aureus bacteria followed by
Gram negative bacteria Escherichia coli and Salmonella thypi at a concentration of 500 mg/ml with an effective
inhibitory diameter of 15.5 mm, Escherichia coli at 14.3 mm, Salmonella typhi at 14, 8 mm.

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Published
2022-07-17
How to Cite
Apriani, A., Masfria, M., & Sitorus, P. (2022). Antibacterial Activity Of Daemonorops Draco (Willd) Blume Fruit Ethanol Extract Against Some Bacterial Pathogens. International Journal of Science, Technology & Management, 3(4), 831-834. https://doi.org/10.46729/ijstm.v3i4.545
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Articles