The Buas Buas Leaf Utilization of Buas Buas Leaf (Premna pubescens Blume) Ethanol Extract as Liquid Soap With Anti-Bacteria Activity

  • Rafita Yuniarti Rafita Universitas Muslim Nusantara Al Washliyah Medan
  • Haris Munandar Nasution Department of Pharmacy, Universitas Muslim Nusantara Al Washliyah, North Sumatera, Indonesia
  • Zulmai Rani Department of Pharmacy, Universitas Muslim Nusantara Al Washliyah, North Sumatera, Indonesia
  • Fahmi Fahmi Department of Pharmacy, Universitas Muslim Nusantara Al Washliyah, North Sumatera, Indonesia
Keywords: Phytochemical screening, liquid soap, antibacterial, Staphylococcus aureus, Premna pubescens Blume

Abstract

The buas buas (Premna pubescens Blume) plant is from the Lamiaceae family. The use of ethanol extract of buas buas leaf (Premna pubescens Blume) as soap is because soap is one of the health products needed by many people to maintain a healthy body. It is used as an antibacterial because buas buas leaves contain secondary metabolites that can be used as antibacterial.The Buas buas leaf Simplicia (Premna pubescens Blume) was extracted using 96% ethanol by maceration and concentrated with a rotary evaporator to evaporate the solvent. The concentrated extract obtained was tested by phytochemical screening, formulated into liquid soap with concentrations of 5%, 10%, 15% and tested for pH, foam height, viscosity, specific gravity and irritation test, and antibacterial activity against staphylococcus aureus bacteria. The results of the phytochemical screening test of the ethanol extract of buas buas leaf (Premna pubescens Blume) contained secondary metabolites in the form of alkaloids, flavonoids, saponins, tannins and steroids/triterpenoids. Liquid soap made with concentrations of 5%, 10%, and 15% has a pH of 10-10.3; foam height 50-90 mm; viscosity 1210-1290 cP; specific gravity 1-1.08 and did not cause irritation to volunteers; and have inhibitory power of 14.2 mm, 15.0 mm, 16.0 mm, and 20.0 mm against Staphylococcus aureus bacteria, respectively.

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References

Arlofa, N. (2015). Test The Content Of Phytochemical Compounds In Durian Skin As An Active Ingredient In Soap Making. International Journal of ChemTech Research, 1(1), 18-22.

Depkes RI. (1979). Pharmacopoeia Edition III. Jakarta: Departemen Kesehatan RI.

Ditjen POM. (1995). Materia Medika Indonesia Jilid VI. Jakarta: Directorate General of Drug and Food Control.

Draelos, Z, D., & Lauren, A.(2006). Cosmetic Formulation of Skin Care Products. New York: Taylor and Francis Group.

Fitriarni, D. (2017). Characterization and antifungal activity of transparent solid soap with the active ingredient of wild wild leaf extract (Premna cordifolia, Linn). Kalimantan barat : Politeknik Negeri Ketapang.

Harborne, J.B. (1987). Phytochemical Methods (Guide to Modern Ways of Analyzing Plants) Second Issue. Bandung: ITB.

Mia, A.L., Mukarlina., et al. (2014). Activity Test of Methanol and n-Hexane Extracts of Wild Leaves (Premna serratifolia Linn.) on Dengue Fever (Aedes aegypti Linn.) Mosquito Larvae. Jurnal Protobiont.hal:247– 251

Morales, G., Sierra, dkk . (2003). Secondary Metabolites From Four Medicinal Plants From Northen Chile, Antimicrobial Activity dan Bioticity Against Artemia salina. Jorunal Chile Chem : (48) 2.

Prasetyawan, A. (2011). Antimicrobial Activity of Senggani (Melastoma affine D. Don) Leaf Ethanol Extract against Staphylococcus Aureus, E. Coli, and C. Albicans. Essay. Universitas Muhammadiyah. Surakarta

Restuadi, M. (2015). Study of the immunosimulant activity of wild wild leaf (Premna pubescens Blume). Essay. Universitas Sumatera Utara. Medan

SNI 06-3532-1994. (1994). Bath soap. National Standardization Agency.

Suresh, M., Babu, K., & Sitram, B. (2013). In Vitro Evaluation Of Antibacterial Activity Of Five Indigenous Plants Extract Against Five Bacterial Pathogens Of Human.International Journal of Pharmacy and Pharmaceutical Science, 5(4), 679-684.

Wahyuni, S. Mukarlina., Ari,H.Y, (2014). Antifungal activity of methanol extract of wild savage leaf (Premna serratifollia) against the fungus Diplodia sp. In Siamese orange (Citrusnobilis var. Microparpa). Jurnal Potobiont.3(2): 274-279.

Wasiaturrahmah, Y., & Jannah, R. (2018). Gel Hand Formulation and Physical Properties TestSanitizer From Bay Leaf Extract (Syzygium polyanthum). Borneo Journal Of Pharmascientech. 2(2), 87– 94.

Wasitaatmadja. (1997). Medical Cosmetics Guide. Jakarta : UI Press.

Widiyaastuti, G. (2017). The effect of wildbuas leaf extract (Premna pubescens Blume) on the growth of Staphylococcus aureus bacteria in vitro. Medan : Universitas Negeri Medan.

Published
2022-05-19
How to Cite
Rafita, R. Y., Munandar Nasution, H., Rani, Z., & Fahmi, F. (2022). The Buas Buas Leaf Utilization of Buas Buas Leaf (Premna pubescens Blume) Ethanol Extract as Liquid Soap With Anti-Bacteria Activity. International Journal of Science, Technology & Management, 3(3), 733-743. https://doi.org/10.46729/ijstm.v3i3.510
Section
Articles